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0}.is-loading{color:#b9d8eb}.is-success{color:#66e6bb}.is-error{color:#ff9eaa}.honeypot{position:absolute!important;left:-10000px!important;width:1px!important;height:1px!important;overflow:hidden!important;opacity:0!important;pointer-events:none!important}.path{position:relative}.path:before{content:"";position:absolute;left:24px;top:70px;bottom:-22px;width:1px;background:linear-gradient(var(--cyan),transparent)}.path:last-child:before{display:none}.path-dot{width:48px;height:48px;border-radius:50%;display:grid;place-items:center;border:1px solid rgba(97,231,255,.4);background:#061526;color:var(--cyan);position:relative;z-index:1}.modal{position:fixed;inset:0;background:rgba(0,0,0,.72);backdrop-filter:blur(10px);z-index:100;display:none;padding:20px;overflow:auto}.modal.open{display:grid;place-items:center}.modal-card{width:min(760px,100%);background:#071525;border:1px solid rgba(97,231,255,.3);border-radius:24px;padding:30px;position:relative;box-shadow:0 40px 120px 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var(--line);border-radius:15px;padding:14px;flex-direction:column;min-width:210px}.navlinks.open{display:flex}.menu{display:block}.grid-3,.grid-4{grid-template-columns:repeat(2,minmax(0,1fr))}.publication{grid-template-columns:1fr}.section-head{display:block}.metric-band{grid-template-columns:repeat(2,1fr)}.metric:nth-child(2){border-right:0}.metric:nth-child(-n+2){border-bottom:1px solid var(--line)}}@media(max-width:620px){h1{font-size:50px}.hero-content{padding:60px 0 75px}.grid-2,.grid-3,.grid-4,.footer-grid{grid-template-columns:1fr}.metric{border-right:0!important}.metric-band{grid-template-columns:1fr 1fr}.flow-step{min-width:145px}.form-shell{padding:20px}.nav{height:68px}.hero{min-height:calc(100vh - 68px)}}

/* 2.5 cinematic UX layer */
.hero-command{position:absolute;right:5%;top:50%;transform:translateY(-45%);width:min(430px,38vw);z-index:2;padding:18px;border:1px solid rgba(97,231,255,.22);border-radius:24px;background:linear-gradient(145deg,rgba(3,14,28,.48),rgba(3,9,20,.22));backdrop-filter:blur(8px);box-shadow:0 35px 100px rgba(0,0,0,.45)}
.command-image{height:235px;border-radius:18px;background:url('/assets/hero-biomedica.png') center/cover;position:relative;overflow:hidden;border:1px solid rgba(97,231,255,.16)}
.command-image:after{content:"";position:absolute;inset:0;background:linear-gradient(180deg,transparent 35%,rgba(3,9,20,.88));}
.command-caption{position:absolute;z-index:1;left:18px;right:18px;bottom:15px}.command-caption strong{display:block;font-size:18px}.command-caption span{font-size:12px;color:#a9c2d6}
.command-line{display:flex;justify-content:space-between;gap:12px;margin-top:12px;padding-top:12px;border-top:1px solid var(--line);font-size:11px;color:#9eb4c9;text-transform:uppercase;letter-spacing:.12em}.command-line b{color:var(--cyan);font-weight:700}
.signal-grid{display:grid;grid-template-columns:1.1fr .9fr;gap:18px}.signal-visual{min-height:390px;border-radius:26px;position:relative;overflow:hidden;background:url('/assets/hero-biomedica.png') center/cover;border:1px solid var(--line);box-shadow:var(--shadow)}.signal-visual:after{content:"";position:absolute;inset:0;background:linear-gradient(180deg,rgba(3,9,20,.08),rgba(3,9,20,.88))}.signal-visual-copy{position:absolute;z-index:1;left:28px;right:28px;bottom:28px}.signal-visual-copy h3{font-size:30px;letter-spacing:-.03em}.signal-visual-copy p{color:#b9cad8;max-width:560px}
.choice-card{cursor:pointer;position:relative;overflow:hidden}.choice-card.selected{border-color:rgba(97,231,255,.72);box-shadow:0 0 0 1px rgba(97,231,255,.22),0 28px 80px rgba(0,0,0,.45)}.choice-card.selected:after{content:"✓";position:absolute;right:18px;top:16px;color:var(--cyan);font-weight:900}.choice-card small{display:block;color:#7891a7;margin-top:10px}.form-intro{display:flex;align-items:center;gap:14px;margin-bottom:22px}.form-intro .step{width:42px;height:42px;border-radius:50%;display:grid;place-items:center;background:rgba(97,231,255,.08);border:1px solid rgba(97,231,255,.28);color:var(--cyan);font-weight:800}.form-note{font-size:12px;color:#8198ab;margin-top:10px}.form-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:16px}.form-grid>*{min-width:0}.form-grid .full{grid-column:1/-1}.form-control{box-sizing:border-box;min-width:0;display:block}.hero + section{background:linear-gradient(180deg,rgba(4,15,28,.15),transparent)}
.research-strip{display:flex;align-items:center;justify-content:space-between;gap:20px;padding:18px 20px;border:1px solid var(--line);border-radius:18px;background:rgba(7,20,36,.58)}.research-strip b{font-size:13px}.research-strip span{font-size:12px;color:var(--muted)}
@media(max-width:980px){.hero-command{position:relative;right:auto;top:auto;transform:none;width:min(680px,92%);margin:0 auto 55px}.hero{display:block;padding-top:35px}.hero-content{padding-top:40px}.signal-grid{grid-template-columns:1fr}}
@media(max-width:620px){.hero-command{width:100%;margin-bottom:25px}.command-image{height:205px}.form-grid{grid-template-columns:1fr}.form-grid .full{grid-column:auto}.research-strip{align-items:flex-start;flex-direction:column}}
@media(prefers-reduced-motion:reduce){*,*::before,*::after{scroll-behavior:auto!important;animation:none!important;transition:none!important}.reveal{opacity:1;transform:none}}

/* 2.6 quality layer: visible scientific imagery, accessibility and interaction */
.skip-link{position:fixed;left:14px;top:12px;z-index:1000;transform:translateY(-180%);background:#e9fbff;color:#03111e;padding:10px 14px;border-radius:10px;font-weight:800;box-shadow:0 10px 30px rgba(0,0,0,.35)}
.skip-link:focus{transform:none}
body:before{content:"";position:fixed;inset:0;z-index:-2;background:radial-gradient(circle at 82% 22%,rgba(74,173,255,.10),transparent 28%),url('/assets/hero-biomedica.png') right center/cover no-repeat;opacity:.075;pointer-events:none}
body:after{content:"";position:fixed;inset:0;z-index:-1;background:linear-gradient(90deg,var(--bg) 0%,rgba(3,9,20,.96) 46%,rgba(3,9,20,.84) 100%);pointer-events:none}
main{position:relative}
main>section:first-child:not(.hero){overflow:hidden}
main>section:first-child:not(.hero):before{content:"";position:absolute;right:-12%;top:0;width:58%;height:100%;background:url('/assets/hero-biomedica.png') center/cover no-repeat;opacity:.13;mask-image:linear-gradient(90deg,transparent 0%,#000 48%,#000 100%);-webkit-mask-image:linear-gradient(90deg,transparent 0%,#000 48%,#000 100%);pointer-events:none}
main>section:first-child:not(.hero)>*{position:relative;z-index:1}
.scientific-badge{display:inline-flex;align-items:center;gap:8px;border:1px solid rgba(97,231,255,.25);background:rgba(5,18,33,.66);border-radius:999px;padding:7px 11px;color:#aeeeff;font-size:11px;letter-spacing:.08em;text-transform:uppercase}
.scientific-badge:before{content:"";width:7px;height:7px;border-radius:50%;background:#65e6bd;box-shadow:0 0 14px #65e6bd}
.form-control:invalid:not(:placeholder-shown){border-color:rgba(255,130,145,.55)}
.form-control:valid:not(:placeholder-shown){border-color:rgba(101,230,189,.25)}
.btn:focus-visible,.navlinks a:focus-visible,.form-control:focus-visible,.menu:focus-visible{outline:3px solid rgba(97,231,255,.48);outline-offset:3px}
@media(max-width:900px){main>section:first-child:not(.hero):before{width:100%;opacity:.08}}

/* 2.6.2 accessibility + visual correction */
.skip-link{position:fixed;left:16px;top:14px;z-index:1000;transform:translateY(-180%);opacity:0;pointer-events:none;background:#e9fbff;color:#03111e;padding:11px 15px;border-radius:10px;font-weight:800;box-shadow:0 10px 30px rgba(0,0,0,.35);transition:transform .18s ease,opacity .18s ease}
.skip-link:focus,.skip-link:focus-visible{transform:translateY(0);opacity:1;pointer-events:auto;outline:3px solid rgba(97,231,255,.7);outline-offset:3px}
#contenido:focus{outline:none}
.hero-content>h1,.hero-content>.lead,.hero-content>.hero-actions,.hero-content>.hero-proof{max-width:760px}
.hero-command{width:min(500px,42%);right:0;top:50%;transform:translateY(-50%);padding:16px;background:linear-gradient(145deg,rgba(3,14,28,.62),rgba(3,9,20,.28));box-shadow:0 35px 110px rgba(0,0,0,.52),0 0 70px rgba(97,231,255,.08)}
.command-image{height:310px;box-shadow:inset 0 0 80px rgba(3,9,20,.18)}
.hero:before{background-image:linear-gradient(90deg,rgba(3,9,20,.99) 0%,rgba(3,9,20,.91) 30%,rgba(3,9,20,.35) 58%,rgba(3,9,20,.20) 82%,rgba(3,9,20,.48) 100%),linear-gradient(180deg,rgba(3,9,20,.02),rgba(3,9,20,.62)),url('/assets/hero-biomedica.png');background-position:center right}
.hero:after{background:linear-gradient(115deg,transparent 0 45%,rgba(97,231,255,.08),transparent 78%)}
@media(max-width:980px){.hero-content{width:min(1180px,92%)}.hero-command{position:relative;right:auto;top:auto;transform:none;width:min(680px,100%);margin:55px 0 0 auto}.command-image{height:260px}.hero-content>h1,.hero-content>.lead,.hero-content>.hero-actions,.hero-content>.hero-proof{max-width:760px}}
@media(max-width:620px){.hero-command{width:100%;margin-top:32px}.command-image{height:220px}.hero-content{padding:55px 0 70px}}
@media(prefers-reduced-motion:reduce){html{scroll-behavior:auto}.reveal{opacity:1;transform:none;transition:none}.pulse{animation:none}.btn,.card.interactive{transition:none}.skip-link{transition:none}}


/* 2.6.3 visual hardening: explicit hero image + stable fallback metrics */
.hero{isolation:isolate;background:#030914;position:relative;}
.hero-bg-img{position:absolute;inset:0;width:100%;height:100%;object-fit:cover;object-position:center right;z-index:0;display:block;filter:saturate(1.08) contrast(1.03);}
.hero-overlay{position:absolute;inset:0;z-index:1;pointer-events:none;background:linear-gradient(90deg,rgba(3,9,20,.985) 0%,rgba(3,9,20,.90) 28%,rgba(3,9,20,.42) 57%,rgba(3,9,20,.18) 80%,rgba(3,9,20,.48) 100%),linear-gradient(180deg,rgba(3,9,20,.06),rgba(3,9,20,.72));}
.hero-content{z-index:2;}
.hero-command,.hero-command *{z-index:3;}
.metric b{font-variant-numeric:tabular-nums;white-space:nowrap;}
@media(max-width:980px){.hero-bg-img{object-position:65% center;opacity:.82}.hero-overlay{background:linear-gradient(180deg,rgba(3,9,20,.78),rgba(3,9,20,.93)),linear-gradient(90deg,rgba(3,9,20,.82),rgba(3,9,20,.35));}}
@media(max-width:620px){.hero-bg-img{object-position:62% center;opacity:.70}.hero-overlay{background:linear-gradient(180deg,rgba(3,9,20,.82),rgba(3,9,20,.95));}}

/* 2.6.5 — Scientific Hero / Evidence Panel */
.evidence-panel{padding:20px!important;background:linear-gradient(145deg,rgba(3,15,29,.82),rgba(3,9,20,.66))!important;border-color:rgba(97,231,255,.30)!important;backdrop-filter:blur(16px)!important;box-shadow:0 35px 110px rgba(0,0,0,.56),0 0 60px rgba(97,231,255,.07)!important}
.evidence-head{display:flex;align-items:center;justify-content:space-between;gap:18px;padding-bottom:16px;border-bottom:1px solid rgba(145,194,225,.16)}
.evidence-head .smallcaps{display:block;font-size:9px;margin-bottom:4px}.evidence-head strong{font-size:21px;letter-spacing:-.02em}.status-dot{width:10px;height:10px;border-radius:50%;background:var(--cyan);box-shadow:0 0 0 5px rgba(97,231,255,.08),0 0 18px rgba(97,231,255,.75);flex:none}
.evidence-flow{display:flex;align-items:center;justify-content:space-between;gap:5px;flex-wrap:wrap;padding:18px 0;border-bottom:1px solid rgba(145,194,225,.16);font-size:9px;letter-spacing:.12em;color:#c7d9e8}.evidence-flow span{padding:6px 7px;border:1px solid rgba(97,231,255,.16);border-radius:7px;background:rgba(97,231,255,.035)}.evidence-flow i{font-style:normal;color:var(--cyan);font-size:12px}
.evidence-metrics{display:grid;grid-template-columns:1fr 1fr;gap:0;margin-top:16px}.evidence-metrics>div{padding:13px 12px;border-right:1px solid rgba(145,194,225,.12);border-bottom:1px solid rgba(145,194,225,.12)}.evidence-metrics>div:nth-child(2n){border-right:0}.evidence-metrics>div:nth-child(n+3){border-bottom:0}.evidence-metrics b{display:block;font-size:23px;letter-spacing:-.035em;color:#effaff}.evidence-metrics span{display:block;font-size:10px;color:#8fa8bc;text-transform:uppercase;letter-spacing:.08em;margin-top:2px}.evidence-panel .command-line{margin-top:14px}
@media(max-width:980px){.evidence-panel{margin-top:45px}.evidence-flow{justify-content:flex-start}}
@media(max-width:620px){.evidence-panel{padding:16px!important}.evidence-flow span{font-size:8px}.evidence-metrics b{font-size:20px}}